Certain leftover debug triggers can be used to skip challenges or boss fights.
When Heavy Iron was developing BfBB, they used debug triggers to quickly and easily test end conditions for certain tasks in the game. However when the game was released, some of these triggers were left in and active. There are four useful debug triggers used in the speedruns. Three are for boss-fights and one is for the Rock Bottom Art. The bossfight triggers are invisible boxes that you have to touch, while the art trigger is a purple shiny object.